Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results.

Autor: Hughes TP; Division of Haematology, SA Pathology and South Australian Health and Medical Research Institute, University of Adelaide, Adelaide, South Australia, Australia., Leber B; Clinical Pathology, McMaster University, Hamilton, Ontario, Canada., Cervantes F; Department of Hematology, Hospital Clinic, IDIBAPS, University of Barcelona, Barcelona, Spain., Spector N; Departamento de Clínica Médica/FM, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil., Pasquini R; Division of Hematology and Medical Oncology, Federal University of Paraná, Curitiba, Brazil., Clementino NCD; Hospital Das Clinicas da UFMG, Belo Horizonte, Brazil., Schwarer AP; Department of Hematology, Alfred Hospital, Melbourne, Victoria, Australia., Dorlhiac-Llacer PE; Department of Hematology, Hospital das Clinicas FMUSP, São Paulo, Brazil., Mahon FX; Laboratoire Hématopoïèse Leucémique et Cible Thérapeutique, Inserm U1035, Université Victor Ségalen, Bordeaux, France., Rea D; Unité de Thérapie Cellulaire et Clinique Transfusionnelle, Service des Maladies du Sang et EA3518, Hôpital Saint-Louis, Paris, France., Guerci-Bresler A; Department of Hematology, Brabois Hospital, Vandoeuvre-lès-Nancy, Vandoeuvre, France., Kamel-Reid S; Clinical Laboratory Genetics, Genome Diagnostics, University Health Network, Toronto General Hospital, Toronto, Ontario, Canada., Bendit I; Hematology Unit, Faculty of Medicine, University of São Paulo, São Paulo, Brazil., Acharya S; Novartis Healthcare Pvt Ltd, Hyderabad, India., Glynos T; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Dalal D; Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA., Branford S; Leukaemia Unit, Centre for Cancer Biology, SA Pathology, University of South Australia and University of Adelaide, Adelaide, South Australia, Australia., Lipton JH; Blood and Marrow Transplant Service, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
Jazyk: angličtina
Zdroj: Leukemia [Leukemia] 2017 Nov; Vol. 31 (11), pp. 2529-2531. Date of Electronic Publication: 2017 Aug 03.
DOI: 10.1038/leu.2017.247
Databáze: MEDLINE