Prevalence and determinants of seborrhoeic dermatitis in a middle-aged and elderly population: the Rotterdam Study.

Autor: Sanders MGH; Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands., Pardo LM; Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Ginger RS; Unilever Research and Development, Colworth Science Park, Sharnbrook, U.K., Nijsten T; Department of Dermatology, Erasmus Medical Center, Rotterdam, the Netherlands.
Jazyk: angličtina
Zdroj: The British journal of dermatology [Br J Dermatol] 2018 Jan; Vol. 178 (1), pp. 148-153. Date of Electronic Publication: 2017 Dec 08.
DOI: 10.1111/bjd.15908
Abstrakt: Background: Seborrhoeic dermatitis is a chronic relapsing inflammatory skin disease with unclear pathophysiological mechanisms.
Objectives: To establish which lifestyle and physiological determinants are associated with seborrhoeic dermatitis.
Methods: Seborrhoeic dermatitis was diagnosed by a trained physician during a full-body skin examination within the Rotterdam Study, a prospective population-based cohort study in middle-aged and elderly people. The current design is a comparative cross-sectional study embedded in the Rotterdam Study. Potential factors were identified from the literature and analysed in a multivariable logistic regression, including: age, sex, obesity, skin colour, stress, depression, education level, hypertension, climate, xerosis cutis, alcohol and tobacco use.
Results: Of the 5498 participants, 788 participants were diagnosed with seborrhoeic dermatitis (14·3%). We found associations between seborrhoeic dermatitis and male sex [adjusted odds ratio (OR) 2·09, 95% confidence interval (CI) 1·77-2·47], darker skin (adjusted OR 0·39, 95% CI 0·22-0·69), season (summer vs. winter: adjusted OR 0·63, 95% CI 0·48-0·82) and generalized xerosis cutis (adjusted OR 1·41, 95% CI 1·11-1·80).
Conclusions: Seborrhoeic dermatitis is one of the most common inflammatory dermatoses in middle-aged and elderly individuals, especially during winter. Men, and people with a light and dry skin were most likely to have seborrhoeic dermatitis.
(© 2017 British Association of Dermatologists.)
Databáze: MEDLINE
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