| Autor: |
Krivorotov AA, Shmal'ko IuP, Pridatko OE, Smelkova MI, Grinzhevskaia SN |
| Jazyk: |
ruština |
| Zdroj: |
Voprosy onkologii [Vopr Onkol] 1987; Vol. 33 (5), pp. 33-7. |
| Abstrakt: |
Such neurohumoral factors of antitumor resistance regulation as catecholamines, corticosteroids and cholinergic mechanisms were studied in tissues of breast cancer patients. Tissue adjacent to tumor revealed elevated concentrations of 11-hydroxycorticosteroids and adrenaline matched by an increased release of norepinephrine which greatly depended on weakened cholinergic influences. These disturbances were pronounced in stages I and II tumors and, particularly, in infiltrating scirrhous cancer. Disbalance in neurohumoral factor distribution between normal and altered tissues may boost tumor recurrence and metastatic spread. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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