Understanding Simple Cystectomy for Benign Disease: A Unique Patient Cohort With Significant Risks.

Autor: Aisen CM; Department of Urology, Columbia University, New York, NY. Electronic address: cmm2236@cumc.columbia.edu., Lipsky MJ; Department of Urology, Columbia University, New York, NY., Tran H; Department of Urology, Columbia University, New York, NY., Chung DE; Department of Urology, Columbia University, New York, NY.
Jazyk: angličtina
Zdroj: Urology [Urology] 2017 Dec; Vol. 110, pp. 239-243. Date of Electronic Publication: 2017 Aug 26.
DOI: 10.1016/j.urology.2017.07.002
Abstrakt: Objective: To explore patient characteristics and complications of simple cystectomy for benign disease. A secondary objective was to compare these parameters to those in radical cystectomy.
Methods: Current Procedural Terminology codes were used to identify patients within the National Surgical Quality Improvement Program who underwent cystectomy (2005-2014). International Classification of Disease, Ninth Revision, codes were used to classify patients with benign or malignant diagnoses. Perioperative complications (30 days) were identified and logistic regression analysis was used to identify factors associated with morbidity.
Results: We identified 389 patients who had a cystectomy for benign diagnosis. A total of 235 patients (60.4%) had complications. The most frequently reported complication was bleeding (requiring a transfusion within 72 hours) in 150 patients (38.6%). Other complications were wound infection (63, 16.2%), respiratory complication (29, 7.5%), wound dehiscence (8, 2.1%), renal complication (9, 2.3%), cardiovascular complication (6, 1.5%), and postoperative deep vein thrombosis (8; 2.1). On multivariate analysis, diabetes (odds ratio 1.9, P = .04) and smoking (odds ratio 1.8, P = .03) were associated with increased odds of any complication. Compared with those with cystectomy for malignancy, this cohort was younger, with higher American Society of Anesthesiologists scores, and chronic kidney disease stages, and the complication risk was similar (60.4% vs 57.7%, P = .3).
Conclusion: Our data suggest that the benign and radical cystectomy patients are different patient populations, with benign patients being younger with a higher American Society of Anesthesiologists class. Even in benign disease, cystectomy is not without risk, and patients should be counseled accordingly.
(Copyright © 2017 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: