Nocturnal motor activity and light exposure: Objective actigraphy-based marks of melancholic and non-melancholic depressive disorder. Brief report.

Autor: Tonon AC; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre (HCPA), Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil. Electronic address: andrectonon@gmail.com., Fuchs DFP; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre (HCPA), Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil., Barbosa Gomes W; Laboratório de Fenomenologia Experimental e Cognição, Instituto de Psicologia, Psicologia, Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2600, Porto Alegre, RS, Brazil., Levandovski R; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre (HCPA), Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil., Pio de Almeida Fleck M; Programa de Transtornos de Humor do Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil., Hidalgo MPL; Laboratório de Cronobiologia e Sono, Hospital de Clínicas de Porto Alegre (HCPA), Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2350, Porto Alegre, RS, Brazil., da Silva Alencastro L; Laboratório de Fenomenologia Experimental e Cognição, Instituto de Psicologia, Psicologia, Federal University of Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2600, Porto Alegre, RS, Brazil.
Jazyk: angličtina
Zdroj: Psychiatry research [Psychiatry Res] 2017 Dec; Vol. 258, pp. 587-590. Date of Electronic Publication: 2017 Aug 19.
DOI: 10.1016/j.psychres.2017.08.025
Abstrakt: Differentiation of melancholic (MEL) and non-melancholic (N-MEL) depression results from subjective assessment of psychomotor disturbance, which obscures their accurate diagnosis. CORE instrument assigned participants with severe or refractory depression to MEL or N-MEL group. Participants underwent 7 days of actigraphy. Data was fitted to a cosinusoidal curve corresponding to a 24-h rhythm. Nocturnal activity was significantly higher in N-MEL. ROC curve shows that average night activity discriminate participants with 71% sensitivity and 100% specificity (area under the curve = 0.84). Actigraphy contribute to the objective differentiation of depression subtypes, and have implications for research on their neurobiology and clinical management.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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