Clinicopathological characteristics and outcomes of squamous cell carcinoma of the tongue in different age groups.

Autor: Zhang YY; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China., Wang DC; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China., Su JZ; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China., Jia LF; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.; Central Laboratory, Peking University School and Hospital of Stomatology, Beijing, China., Peng X; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China., Yu GY; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China.
Jazyk: angličtina
Zdroj: Head & neck [Head Neck] 2017 Nov; Vol. 39 (11), pp. 2276-2282. Date of Electronic Publication: 2017 Aug 26.
DOI: 10.1002/hed.24898
Abstrakt: Background: The clinicopathological features and outcomes of squamous cell carcinoma (SCC) of the tongue in patients of different age groups remain debatable.
Methods: Medical records of 457 patients with tongue SCC were reviewed, grouped by age, followed up, and compared.
Results: Sex and TNM stage showed no intergroup differences. Tongue SCC in patients ≤30 years had the most advanced TNM classification and greatest proportion of poorly differentiation tumors. Both disease-free survival (DFS) and disease-specific survival (DSS) showed no statistically significant difference between the youngest and the oldest groups (P = .605 and P = .520). However, there was a tendency of higher death rate caused by recurrence or metastasis in the youngest group compared with the others (91.7% vs 75.4% and 77.4%).
Conclusion: Young patients had a tendency of higher death rate caused by recurrence or metastasis than middle-age and older patients; therefore, a larger case sample is needed for further confirmation.
(© 2017 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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