Emerging role of Actinomyces meyeri in brain abscesses: A case report and literature review.

Autor: Vazquez Guillamet LJ; Department of Medicine, Yale New Haven Health-Bridgeport Hospital, 267 Grant St., Bridgeport, CT, 06610, USA., Malinis MF; Section of Infectious Diseases, Yale School of Medicine, New Haven, CT USA., Meyer JP; Yale AIDS Program, New Haven, CT, USA.
Jazyk: angličtina
Zdroj: IDCases [IDCases] 2017 Jul 20; Vol. 10, pp. 26-29. Date of Electronic Publication: 2017 Jul 20 (Print Publication: 2017).
DOI: 10.1016/j.idcr.2017.07.007
Abstrakt: We describe a case of a 29-year-old man from Pakistan who presented with progressive neurologic symptoms over 1 week and was found to have a right parietal cerebral abscess. Neurosurgical drainage cultures showed growth of Actinomyces meyeri , Streptococcus intermedius , and Parvimonas micra . An abscessed molar was identified as the likely port of entry and was extracted. The patient was treated with metronidazole, vancomycin, and doxycycline because of prior anaphylaxis to penicillin. At 6-month follow-up, repeat magnetic resonance imaging showed no signs of residual abscess. Culture-independent identification techniques (e.g., ribosomal sequencing) increasingly identify Actinomyces meyeri as a causative agent and significant pathogen in spontaneous brain abscesses. As understanding about Actinomyces meyeri's prevalence and pathogenesis improves, questions arise about optimal treatment strategy, which we discuss based on a literature review.
Databáze: MEDLINE