Is Fasting for Ramadan Safe in Patients with Mechanical Cardiac Valves?

Autor:	Yildirim E; Elazığ Education and Research Hospitall, Elazig, Turkey. Electronic correspondence: ersinyil44@gmail.com., Secen O; Elazığ Education and Research Hospitall, Elazig, Turkey., Uku O; Elazığ Education and Research Hospitall, Elazig, Turkey., Nail Bilen M; Elazığ Education and Research Hospitall, Elazig, Turkey., Kutlu Karadag M; Elazığ Education and Research Hospitall, Elazig, Turkey.
Jazyk:	angličtina
Zdroj:	The Journal of heart valve disease [J Heart Valve Dis] 2017 Mar; Vol. 26 (2), pp. 200-204.
Abstrakt:	Background and Aim of the Study: The study aim was to investigate the safety and effects of fasting during Ramadan on the International Normalized Ratio (INR) in patients with mechanical cardiac valves. Methods: A total of 105 patients admitted to the authors' hospital between June and October 2015, who had history of prosthetic valve replacement, was investigated. The patients were allocated to two groups: those fasting during Ramadan (n = 42) and those not fasting (n = 63). All patients were examined by a cardiologist, and the clinical findings and complaints for the past three months were evaluated. The INR, complete blood count (CBC) and a basic biochemical panel were monitored for all patients. Results: The mean corpuscular volume (MCV) of the fasting group was significantly higher than that of the non- fasting group (87.59 ± 6.39 (μm3) versus 84.28 ± 6.387 (μm3); p = 0.011). Other CBC parameters and basic biochemical values did not differ significantly different between groups. Neither were significant differences noted in INR values during Ramadan (fasting group 2.87 ± 0.97; non-fasting group 2.73 ± 0.78; p = 0.50) and at routine control one month later (fasting group 3.07 ± 1.55; non-fasting group 2.94 ± 1.03; p = 0.601). No significant differences related to increased rates of hospitalization, valvular dysfunction on echocardiography, thrombus, embolism, bleeding and clinical complaints were identified between the groups. Conclusions: Fasting during Ramadan had no adverse effects on the INR of patients, and appears to be safe for patients with mechanical prosthetic cardiac valves.
Databáze:	MEDLINE
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