Multimodal Neuroimaging in Schizophrenia: Description and Dissemination.

Autor: Aine CJ; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA.; Department of Radiology, University of New Mexico SOM, Albuquerque, NM, USA., Bockholt HJ; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA.; Advanced Biomedical Informatics, LLC, Coralville, IA, USA.; Department of Psychiatry, University of Iowa, SOM, Iowa City, IA, USA., Bustillo JR; Department of Psychiatry, University of New Mexico SOM, Albuquerque, NM, USA., Cañive JM; Department of Psychiatry, University of New Mexico SOM, Albuquerque, NM, USA.; New Mexico VA Health Care System, Albuquerque, NM, USA., Caprihan A; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Gasparovic C; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Hanlon FM; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Houck JM; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Jung RE; Department of Neurosurgery, University of New Mexico SOM, Albuquerque, NM, USA., Lauriello J; Department of Psychiatry, University of Missouri Health Care, Columbia, MO, USA., Liu J; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Mayer AR; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Perrone-Bizzozero NI; Department of Neurosciences, University of New Mexico SOM, Albuquerque, NM, USA., Posse S; Department of Neurology, University of New Mexico SOM, Albuquerque, NM, USA.; Department of Electrical and Computer Engineering, Albuquerque, NM, USA.; Department of Physics and Astronomy, Albuquerque, NM, USA., Stephen JM; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA., Turner JA; Department of Psychology, Georgia State University, Atlanta, GA, USA., Clark VP; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA.; Department of Neurosciences, University of New Mexico SOM, Albuquerque, NM, USA.; Department of Psychology, University of New Mexico, Albuquerque, NM, USA., Calhoun VD; The Mind Research Network, 1101 Yale Blvd NE, Albuquerque, NM, 87106, USA. vcalhoun@mrn.org.; Department of Psychiatry, University of New Mexico SOM, Albuquerque, NM, USA. vcalhoun@mrn.org.; Department of Neurosciences, University of New Mexico SOM, Albuquerque, NM, USA. vcalhoun@mrn.org.; Department of Electrical and Computer Engineering, Albuquerque, NM, USA. vcalhoun@mrn.org.
Jazyk: angličtina
Zdroj: Neuroinformatics [Neuroinformatics] 2017 Oct; Vol. 15 (4), pp. 343-364.
DOI: 10.1007/s12021-017-9338-9
Abstrakt: In this paper we describe an open-access collection of multimodal neuroimaging data in schizophrenia for release to the community. Data were acquired from approximately 100 patients with schizophrenia and 100 age-matched controls during rest as well as several task activation paradigms targeting a hierarchy of cognitive constructs. Neuroimaging data include structural MRI, functional MRI, diffusion MRI, MR spectroscopic imaging, and magnetoencephalography. For three of the hypothesis-driven projects, task activation paradigms were acquired on subsets of ~200 volunteers which examined a range of sensory and cognitive processes (e.g., auditory sensory gating, auditory/visual multisensory integration, visual transverse patterning). Neuropsychological data were also acquired and genetic material via saliva samples were collected from most of the participants and have been typed for both genome-wide polymorphism data as well as genome-wide methylation data. Some results are also presented from the individual studies as well as from our data-driven multimodal analyses (e.g., multimodal examinations of network structure and network dynamics and multitask fMRI data analysis across projects). All data will be released through the Mind Research Network's collaborative informatics and neuroimaging suite (COINS).
Databáze: MEDLINE
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