Retroperitoneal Bleeding: An Experience During Prophylactic Anticoagulation in a Patient With Nephrotic Syndrome.

Autor: Okada M; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Akimoto T; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Kawamata M; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Imai T; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Hishida E; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Kohara M; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Miki A; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Murakami T; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Sugase T; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Masuda T; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Ono Y; Department of Diagnostic Pathology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan., Ueda Y; Department of Diagnostic Pathology, Dokkyo Medical University Koshigaya Hospital, Saitama, Japan., Saito O; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Muto S; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan., Nagata D; Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan.
Jazyk: angličtina
Zdroj: Clinical medicine insights. Case reports [Clin Med Insights Case Rep] 2017 Aug 01; Vol. 10, pp. 1179547617723317. Date of Electronic Publication: 2017 Aug 01 (Print Publication: 2017).
DOI: 10.1177/1179547617723317
Abstrakt: The association between nephrotic syndrome (NS) and a hypercoagulable state has been demonstrated. Controlling the blood clotting activity may therefore be attractive for patients with nephrosis in terms of thromboembolism prophylaxis. We herein report a 75-year-old woman with minimal change disease who developed pains in the right back, groin, and thigh because of retroperitoneal bleeding during prophylactic anticoagulation with unfractionated heparin. Although this procedure has not been accepted as the standard of care for patients with nephrosis, pharmacologic prophylaxis may already be practiced empirically, as in the present patient. We believe that our experience highlights the pitfalls of such a management in patients with nephrosis, implying the need for a diagnostic strategy for identifying those patients with NS who can benefit from prophylactic anticoagulation. Several concerns that emerged in this case are also discussed.
Competing Interests: Declaration of conflicting interests:The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE
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