Evaluation of Cortez OneStep Chlamydia Rapicard™ Insta Test for the Detection of Chlamydia trachomatis in Pregnant Women at Mbare Polyclinic in Harare, Zimbabwe.

Autor:	Stephen S; Department of Medical Microbiology, University of Zimbabwe, College of Health Sciences P.O Box A178, Avondale, Harare, Zimbabwe., Muchaneta-Kubara CGE; Department of Medical Microbiology, University of Zimbabwe, College of Health Sciences P.O Box A178, Avondale, Harare, Zimbabwe., Munjoma MW; Department of Obstetrics and Gynaecology, University of Zimbabwe, College of Health Sciences P.O Box A178, Avondale, Harare, Zimbabwe., Mandozana G; Department of Community Medicine, University of Zimbabwe, College of Health Sciences P.O Box A178, Avondale, Harare, Zimbabwe.
Jazyk:	angličtina
Zdroj:	International journal of MCH and AIDS [Int J MCH AIDS] 2017; Vol. 6 (1), pp. 19-26.
DOI:	10.21106/ijma.150
Abstrakt:	Background: Cervical chlamydia infection poses high risk of pregnancy complications and neonatal infection. Reference methods for the detection of chlamydia infection are not available for routine use in developing countries. Point-of-care (POC) tests can bridge this gap. This study evaluated Cortez Onestep Chlamydia Rapicard™ insta test for the detection of Chlamydia trachomatis in pregnant women at Mbare Polyclinic and determined the prevalence of C. trachomatis . Methods: This was a cross sectional study in 242 pregnant women aged ≥18 years attending their first ANC visit at Mbare polyclinic in Harare, Zimbabwe. Data collection form was used to obtain demographic and predisposing factors to Chlamydia infection and two endocervical swabs were collected from each patient. One specimen was examined by the POC test at the clinic and the other by SDA method in the laboratory. Results: The sensitivity, specificity, positive and negative predictive values of the rapid kit were 71.4%, 99.6%, 90.9% and 98.3% respectively. Prevalence of C. trachomitis was 5.8% by SDA method. Conclusion and Global Health Implications: The kit's sensitivity (71.4%) and specificity (99.6%) implies that the rapid test is an important test which needs further evaluations. The prevalence of C. trichomitis of 5.8% is comparable to studies done elsewhere in Africa. Competing Interests: Conflict of Interest: The authors declare that there is no conflict of interests regarding the publication of this paper.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu