Determination of regulatory ionophore coccidiostat residues in feedstuffs at carry-over levels by liquid chromatography-mass spectrometry.

Autor: Annunziata L; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy., Visciano P; Faculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Stramenga A; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Perugia, Italy., Colagrande MN; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy., Campana G; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy., Scortichini G; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche, Perugia, Italy., Migliorati G; Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise 'G. Caporale', Teramo, Italy., Compagnone D; Faculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2017 Aug 09; Vol. 12 (8), pp. e0182831. Date of Electronic Publication: 2017 Aug 09 (Print Publication: 2017).
DOI: 10.1371/journal.pone.0182831
Abstrakt: In this study samples of feedstuffs were collected from different feed mills and animal farms located in central Italy and analyzed for ionophore coccidiostat residues at carry-over levels by liquid chromatography-mass spectrometry. Since unavoidable cross-contamination of feedstuffs may occur during their production as well as distribution and storage, the collection of samples covered all these different stages. Residues of lasalocid, monensin, salinomycin and maduramicin were detected in 32.4% of samples, both at production and storage level. The maximum content for unavoidable carry-over set by Regulation (EU) No 574/2011 was exceeded in 11.3% of samples. The variability of the results highlighted the different approach of each investigated feed business operator to avoid any cross-contamination in non-target feed. The method developed in this study can be able to detect ionophore coccidiostats at low concentrations consequent to carry-over.
Databáze: MEDLINE
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