Immune Reconstitution Inflammatory Syndrome After DLI in a SCID Patient After Hematopoetic Stem Cell Transplantation.

Autor:	Kocacik Uygun DF; Department of Pediatric Immunology, Antalya Training and Research Hospital., Uygun V; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Antalya Hospital., Daloğlu H; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Antalya Hospital, Antalya., Öztürkmen SI; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Antalya Hospital, Antalya., Karasu GT; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Göztepe Hospital., Hazar V; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Göztepe Hospital, İstanbul, Turkey., Yeşilipek A; Department of Pediatric Bone Marrow Transplantation Unit, MedicalPark Antalya Hospital.
Jazyk:	angličtina
Zdroj:	Journal of pediatric hematology/oncology [J Pediatr Hematol Oncol] 2018 Apr; Vol. 40 (3), pp. e179-e181.
DOI:	10.1097/MPH.0000000000000923
Abstrakt:	Immune reconstitution inflammatory syndrome (IRIS) is a clinical condition emerging after immune recovery of an immunocompromised status, mostly in human immunodeficiency virus infected patients but also in several other settings, such as the recovery from the severe combined immunodeficiency status after hematopoietic stem cell transplantation. Herein, we report a patient transplanted for severe combined immunodeficiency who developed IRIS for 2 times, namely shortly after transplantation and after donor lymphocyte infusion. Pediatric transplant teams need to be aware of the previous IRIS phenomenon of BCG-adenitis while making the decision of donor lymphocyte infusions.
Databáze:	MEDLINE
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