Impact of Exercise Training on Peak Oxygen Uptake and its Determinants in Heart Failure with Preserved Ejection Fraction.

Autor: Tucker WJ; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington,Texas, USA., Nelson MD; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington,Texas, USA., Beaudry RI; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington,Texas, USA., Halle M; Technical University Munich,Munich, Germany., Sarma S; Institute for Exercise and Environmental Medicine,Texas Health Presbyterian Hospital, Dallas.; University of Texas Southwestern Medical Center,Dallas, Texas, USA., Kitzman DW; Wake Forest School of MedicineWinston-Salem, North Carolina, USA., Gerche A; Sport Cardiology, Baker IDI Heart Institute,Melbourne, Victoria, Australia., Haykowksy MJ; College of Nursing and Health Innovation, University of Texas at Arlington, Arlington,Texas, USA.; Sport Cardiology, Baker IDI Heart Institute,Melbourne, Victoria, Australia.
Jazyk: angličtina
Zdroj: Cardiac failure review [Card Fail Rev] 2016 Nov; Vol. 2 (2), pp. 95-101.
DOI: 10.15420/cfr.2016:16:2
Abstrakt: Heart failure with preserved ejection (HFpEF) accounts for over 50 % of all HF cases, and the proportion is higher among women and older individuals. A hallmark feature of HFpEF is dyspnoea on exertion and reduced peak aerobic power (VO 2peak ) secondary to central and peripheral abnormalities that result in reduced oxygen delivery to and/or utilisation by exercising skeletal muscle. The purpose of this brief review is to discuss the role of exercise training to improve VO 2peak and the central and peripheral adaptations that reduce symptoms following physical conditioning in patients with HFpEF.
Competing Interests: Disclosure: DWK is funded by NIH grants R01AG18915; P30AG12232. MJH is funded by the Moritz Chair in Geriatrics in the College of Nursing and Health Innovation at the University of Texas at Arlington. The remaining authors have no conflicts of interest to declare.
Databáze: MEDLINE