Fast analysis of quaternary ammonium pesticides in food and beverages using cation-exchange chromatography coupled with isotope-dilution high-resolution mass spectrometry.

Autor: Nardin T; Centro Trasferimento Tecnologico, Fondazione E. Mach, San Michele all'Adige, Trentino, Italy., Barnaba C; Centro Trasferimento Tecnologico, Fondazione E. Mach, San Michele all'Adige, Trentino, Italy., Abballe F; Thermo Fisher Scientific SpA, Rodano, Milan, Italy., Trenti G; Centro Trasferimento Tecnologico, Fondazione E. Mach, San Michele all'Adige, Trentino, Italy., Malacarne M; Centro Trasferimento Tecnologico, Fondazione E. Mach, San Michele all'Adige, Trentino, Italy., Larcher R; Centro Trasferimento Tecnologico, Fondazione E. Mach, San Michele all'Adige, Trentino, Italy.
Jazyk: angličtina
Zdroj: Journal of separation science [J Sep Sci] 2017 Oct; Vol. 40 (20), pp. 3928-3937. Date of Electronic Publication: 2017 Sep 04.
DOI: 10.1002/jssc.201700579
Abstrakt: A fast separation based on cation-exchange liquid chromatography coupled with high-resolution mass spectrometry is proposed for simultaneous determination of chlormequat, difenzoquat, diquat, mepiquat and paraquat in several food and beverage commodities. Solid samples were extracted using a mixture of water/methanol/formic acid (69.6:30:0.4, v/v/v), while liquid samples were ten times diluted with the same solution. Separation was carried out on an experimental length-modified IonPac CS17 column (2 × 15 mm 2 ) that allowed the use of formic acid and acetonitrile as mobile phase. Detection limits for food and beverage matrices were established at 1.5 μg/L for chlormequat, difenzoquat and mepiquat, and 3 μg/L for diquat and paraquat, while for drinking water a pre-analytical sample concentration allowed detection limits of 9 and 20 ng/L, respectively. Precision, as repeatability (RSD%), ranged from 0.2 to 24%, with a median value of 6%, and trueness, as recovery, ranged from 64 to 118%, with a median value of 96%. The method developed was successfully applied to investigate the presence of herbicide residues in commercial commodities (mineral water, orange juice, beer, tea, green coffee bean, toasted coffee powder, cocoa bean, white corn flour, rice and sugar samples).
(© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
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