| Autor: |
Spencer PS, Roy DN, Ludolph A, Hugon J, Dwivedi MP, Schaumburg HH |
| Jazyk: |
angličtina |
| Zdroj: |
Lancet (London, England) [Lancet] 1986 Nov 08; Vol. 2 (8515), pp. 1066-7. |
| DOI: |
10.1016/s0140-6736(86)90468-x |
| Abstrakt: |
Lathyrism, a form of motoneuron disease induced by excessive consumption of th legume Lathyrus sativus (chickling pea), presents as signs of pyramidal tract involvement. Primate feeding studies show that beta-N-oxalylamino-L-alanine (BOAA), a potent neuroexcitatory aminoacid in the chickling pea, induces corticospinal dysfunction similar to that seen in animals consuming a fortified diet of this legume. BOAA, a potent agonist of the excitatory neurotransmitter glutamate, is likely to be causally associated with lathyrism in man. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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