Human Gut Microbiota: Toward an Ecology of Disease.

Autor: Selber-Hnatiw S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Rukundo B; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ahmadi M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Akoubi H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Al-Bizri H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Aliu AF; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ambeaghen TU; Department of Biology, Concordia UniversityMontréal, QC, Canada., Avetisyan L; Department of Biology, Concordia UniversityMontréal, QC, Canada., Bahar I; Department of Biology, Concordia UniversityMontréal, QC, Canada., Baird A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Begum F; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ben Soussan H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Blondeau-Éthier V; Department of Biology, Concordia UniversityMontréal, QC, Canada., Bordaries R; Department of Biology, Concordia UniversityMontréal, QC, Canada., Bramwell H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Briggs A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Bui R; Department of Biology, Concordia UniversityMontréal, QC, Canada., Carnevale M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Chancharoen M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Chevassus T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Choi JH; Department of Biology, Concordia UniversityMontréal, QC, Canada., Coulombe K; Department of Biology, Concordia UniversityMontréal, QC, Canada., Couvrette F; Department of Biology, Concordia UniversityMontréal, QC, Canada., D'Abreau S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Davies M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Desbiens MP; Department of Biology, Concordia UniversityMontréal, QC, Canada., Di Maulo T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Di Paolo SA; Department of Biology, Concordia UniversityMontréal, QC, Canada., Do Ponte S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Dos Santos Ribeiro P; Department of Biology, Concordia UniversityMontréal, QC, Canada., Dubuc-Kanary LA; Department of Biology, Concordia UniversityMontréal, QC, Canada., Duncan PK; Department of Biology, Concordia UniversityMontréal, QC, Canada., Dupuis F; Department of Biology, Concordia UniversityMontréal, QC, Canada., El-Nounou S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Eyangos CN; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ferguson NK; Department of Biology, Concordia UniversityMontréal, QC, Canada., Flores-Chinchilla NR; Department of Biology, Concordia UniversityMontréal, QC, Canada., Fotakis T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Gado Oumarou H D M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Georgiev M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ghiassy S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Glibetic N; Department of Biology, Concordia UniversityMontréal, QC, Canada., Grégoire Bouchard J; Department of Biology, Concordia UniversityMontréal, QC, Canada., Hassan T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Huseen I; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ibuna Quilatan MF; Department of Biology, Concordia UniversityMontréal, QC, Canada., Iozzo T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Islam S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Jaunky DB; Department of Biology, Concordia UniversityMontréal, QC, Canada., Jeyasegaram A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Johnston MA; Department of Biology, Concordia UniversityMontréal, QC, Canada., Kahler MR; Department of Biology, Concordia UniversityMontréal, QC, Canada., Kaler K; Department of Biology, Concordia UniversityMontréal, QC, Canada., Kamani C; Department of Biology, Concordia UniversityMontréal, QC, Canada., Karimian Rad H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Konidis E; Department of Biology, Concordia UniversityMontréal, QC, Canada., Konieczny F; Department of Biology, Concordia UniversityMontréal, QC, Canada., Kurianowicz S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Lamothe P; Department of Biology, Concordia UniversityMontréal, QC, Canada., Legros K; Department of Biology, Concordia UniversityMontréal, QC, Canada., Leroux S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Li J; Department of Biology, Concordia UniversityMontréal, QC, Canada., Lozano Rodriguez ME; Department of Biology, Concordia UniversityMontréal, QC, Canada., Luponio-Yoffe S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Maalouf Y; Department of Biology, Concordia UniversityMontréal, QC, Canada., Mantha J; Department of Biology, Concordia UniversityMontréal, QC, Canada., McCormick M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Mondragon P; Department of Biology, Concordia UniversityMontréal, QC, Canada., Narayana T; Department of Biology, Concordia UniversityMontréal, QC, Canada., Neretin E; Department of Biology, Concordia UniversityMontréal, QC, Canada., Nguyen TTT; Department of Biology, Concordia UniversityMontréal, QC, Canada., Niu I; Department of Biology, Concordia UniversityMontréal, QC, Canada., Nkemazem RB; Department of Biology, Concordia UniversityMontréal, QC, Canada., O'Donovan M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Oueis M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Paquette S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Patel N; Department of Biology, Concordia UniversityMontréal, QC, Canada., Pecsi E; Department of Biology, Concordia UniversityMontréal, QC, Canada., Peters J; Department of Biology, Concordia UniversityMontréal, QC, Canada., Pettorelli A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Poirier C; Department of Biology, Concordia UniversityMontréal, QC, Canada., Pompa VR; Department of Biology, Concordia UniversityMontréal, QC, Canada., Rajen H; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ralph RO; Department of Biology, Concordia UniversityMontréal, QC, Canada., Rosales-Vasquez J; Department of Biology, Concordia UniversityMontréal, QC, Canada., Rubinshtein D; Department of Biology, Concordia UniversityMontréal, QC, Canada., Sakr S; Department of Biology, Concordia UniversityMontréal, QC, Canada., Sebai MS; Department of Biology, Concordia UniversityMontréal, QC, Canada., Serravalle L; Department of Biology, Concordia UniversityMontréal, QC, Canada., Sidibe F; Department of Biology, Concordia UniversityMontréal, QC, Canada., Sinnathurai A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Soho D; Department of Biology, Concordia UniversityMontréal, QC, Canada., Sundarakrishnan A; Department of Biology, Concordia UniversityMontréal, QC, Canada., Svistkova V; Department of Biology, Concordia UniversityMontréal, QC, Canada., Ugbeye TE; Department of Biology, Concordia UniversityMontréal, QC, Canada., Vasconcelos MS; Department of Biology, Concordia UniversityMontréal, QC, Canada., Vincelli M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Voitovich O; Department of Biology, Concordia UniversityMontréal, QC, Canada., Vrabel P; Department of Biology, Concordia UniversityMontréal, QC, Canada., Wang L; Department of Biology, Concordia UniversityMontréal, QC, Canada., Wasfi M; Department of Biology, Concordia UniversityMontréal, QC, Canada., Zha CY; Department of Biology, Concordia UniversityMontréal, QC, Canada., Gamberi C; Department of Biology, Concordia UniversityMontréal, QC, Canada.
Jazyk: angličtina
Zdroj: Frontiers in microbiology [Front Microbiol] 2017 Jul 17; Vol. 8, pp. 1265. Date of Electronic Publication: 2017 Jul 17 (Print Publication: 2017).
DOI: 10.3389/fmicb.2017.01265
Abstrakt: Composed of trillions of individual microbes, the human gut microbiota has adapted to the uniquely diverse environments found in the human intestine. Quickly responding to the variances in the ingested food, the microbiota interacts with the host via reciprocal biochemical signaling to coordinate the exchange of nutrients and proper immune function. Host and microbiota function as a unit which guards its balance against invasion by potential pathogens and which undergoes natural selection. Disturbance of the microbiota composition, or dysbiosis, is often associated with human disease, indicating that, while there seems to be no unique optimal composition of the gut microbiota, a balanced community is crucial for human health. Emerging knowledge of the ecology of the microbiota-host synergy will have an impact on how we implement antibiotic treatment in therapeutics and prophylaxis and how we will consider alternative strategies of global remodeling of the microbiota such as fecal transplants. Here we examine the microbiota-human host relationship from the perspective of the microbial community dynamics.
Databáze: MEDLINE
Externí odkaz: