Nutraceutical potential of Byrsonima cydoniifolia fruits based on chemical composition, anti-inflammatory, and antihyperalgesic activities.

Autor:	Santos VSD; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Nascimento TV; Laboratório de Farmacologia e Inflamação, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Felipe JL; Laboratório de Farmacologia e Inflamação, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Boaretto AG; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Damasceno-Junior GA; Laboratório de Botânica, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Silva DB; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Toffoli-Kadri MC; Laboratório de Farmacologia e Inflamação, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil., Carollo CA; Laboratório de Produtos Naturais e Espectrometria de Massas, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, Brazil. Electronic address: carlos.carollo@ufms.br.
Jazyk:	angličtina
Zdroj:	Food chemistry [Food Chem] 2017 Dec 15; Vol. 237, pp. 240-246. Date of Electronic Publication: 2017 May 19.
DOI:	10.1016/j.foodchem.2017.05.082
Abstrakt:	In recent years, the fruits of native Brazilian plant species with anti-inflammatory property have gained prominence due to their properties comparable to traditional medicines. This study aimed to chemically characterize and evaluate the anti-inflammatory and antihyperalgesic activity of Byrsonima cydoniifolia fruit, which is widely used to manufacture ice cream and jellies. Our results revealed that the fruit exhibits flavonoid derivatives and stilbenes, as trans-piceatannol and resveratrol, as main secondary metabolites. In mice, the hydroethanolic extract of fruit reduced the edema, migration of polymorphonuclear leukocytes into the peritoneal cavity, as well as abdominal writhings. The results demonstrated, for the first time, the presence of stilbenoids in the Byrsonima genus and the anti-inflammatory and antihyperalgesic effect of Byrsonima cydoniifolia fruits, supporting its potential as a nutraceutical food. (Copyright © 2017 Elsevier Ltd. All rights reserved.)
Databáze:	MEDLINE
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