Assessing the Need for Routine Screening for Mycoplasma genitalium in the Low-risk Female Population: A Prevalence and Co-infection Study on Women from Croatia.

Autor: Ljubin-Sternak S; Clinical Microbiology Department, Teaching Institute of Public Health 'Dr. Andrija Štampar', Zagreb, Croatia.; Medical Microbiology Department, School of Medicine, University of Zagreb, Zagreb, Croatia., Meštrović T; Clinical Microbiology and Parasitology Unit, Polyclinic Dr. Zora Profozić', Zagreb, Croatia., Kolarić B; Epidemiology Department, Teaching Institute of Public Health 'Dr. Andrija Štampar', Zagreb, Croatia.; Social Medicine and Epidemiology Department, Faculty of Medicine, University of Rijeka, Rijeka, Croatia., Jarža-Davila N; Clinical Microbiology Department, Teaching Institute of Public Health 'Dr. Andrija Štampar', Zagreb, Croatia., Marijan T; Clinical Microbiology Department, Teaching Institute of Public Health 'Dr. Andrija Štampar', Zagreb, Croatia., Vraneš J; Clinical Microbiology Department, Teaching Institute of Public Health 'Dr. Andrija Štampar', Zagreb, Croatia.; Medical Microbiology Department, School of Medicine, University of Zagreb, Zagreb, Croatia.
Jazyk: angličtina
Zdroj: International journal of preventive medicine [Int J Prev Med] 2017 Jul 04; Vol. 8, pp. 51. Date of Electronic Publication: 2017 Jul 04 (Print Publication: 2017).
DOI: 10.4103/ijpvm.IJPVM_309_16
Abstrakt: Background: There is an ongoing debate regarding possible cost and benefits, but also harm of universal screening for the emerging sexually transmitted pathogen Mycoplasma genitalium .
Methods: From the initial pool of 8665 samples that were tested, a subset of Chlamydia trachomatis -positive and randomly selected C. trachomatis -negative cervical swabs were further interrogated for M. genitalium by real-time polymerase chain reaction, using a 224 bp long fragment of the glyceraldehyde-3-phosphate dehydrogenase gene.
Results: M. genitalium was detected in 4.8% of C. trachomatis -positive samples and none of C. trachomatis -negative samples. Accordingly, a significant association was shown between M. genitalium and C. trachomatis ( P < 0.01), but also between M. genitalium and Mycoplasma hominis infection ( P < 0.01).
Conclusions: Based on the results, routine screening is recommended only for women with one or more identified risk factors. Moreover, younger age does not represent an appropriate inclusion/exclusion criterion for M. genitalium testing in the low-risk female population.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE
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