Genotoxicity Induced by Dental Materials: A Comprehensive Review.

Autor: Ribeiro DA; Department of Biosciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil daribeiro@unifesp.br.; Department of Pathology, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., Yujra VQ; Department of Pathology, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., DE Moura CFG; Department of Biosciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., Handan BA; Department of Biosciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., DE Barros Viana M; Department of Biosciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., Yamauchi LY; Department of Human Movement Sciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., Castelo PM; Department of Biological Sciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil., Aguiar O Jr; Department of Biosciences, Federal University of São Paulo, UNIFESP, Sao Paolo, Brazil.
Jazyk: angličtina
Zdroj: Anticancer research [Anticancer Res] 2017 Aug; Vol. 37 (8), pp. 4017-4024.
DOI: 10.21873/anticanres.11786
Abstrakt: Genotoxicity is the capacity of an agent to produce damage in the DNA molecule. Considering the strong evidence for a relationship between genetic damage and carcinogenesis, evaluation of genotoxicity induced by dental materials is necessary for elucidating the true health risks to patients and professionals. The purpose of this article was to provide a comprehensive review of genotoxicity induced by dental materials. All published data showed some evidence of genotoxicity, especially related to dental bleaching, restorative materials and endodontic compounds. Certainly, such information will be added to that already established for regulatory purposes as a safe way to promote oral healthcare and prevent oral carcinogenesis.
(Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Databáze: MEDLINE
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