Dynamics of the Pro-Oxidant/Antioxidant System Parameters in Wound Discharge and Plasma in Experimental Purulent Wound during Its Technological Liquid Phase Treatment.

Autor: Bykov IM; Kuban State Medical University, the Ministry of Health of the Russian Federation, Krasnodar, Russia., Basov AA; Kuban State Medical University, the Ministry of Health of the Russian Federation, Krasnodar, Russia. son_sunytch@mail.ru., Malyshko VV; Kuban State Medical University, the Ministry of Health of the Russian Federation, Krasnodar, Russia., Dzhimak SS; Kuban State University, Krasnodar, Russia., Fedosov SR; Kuban State University, Krasnodar, Russia., Moiseev AV; Kuban State Agrarian University, Krasnodar, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Jun; Vol. 163 (2), pp. 268-271. Date of Electronic Publication: 2017 Jul 18.
DOI: 10.1007/s10517-017-3781-3
Abstrakt: The dynamics of the pro-oxidant/antioxidant system of rabbits was studied at the local (in exudate) and systemic (blood) levels during therapy of purulent wounds in liquid medium with the use of a programmed device and the efficiency of the proposed technological method was compared with that of classical methods for the treatment of these wounds. More rapid recovery of the indicators of the pro-oxidant/antioxidant system to physiological values in the postoperative period was observed after treatment by the proposed method (7 days vs. 10 days after standard treatment), these results attest to strengthening of the adaptation potential in laboratory animals. The intensity of free radical oxidation in the exudate decreased by 26.6% in animals treated by the technological method. These data indicated acceleration of the regenerative processes at the local level.
Databáze: MEDLINE
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