First Degree Burn

Autor: Pencle FJ, Mowery ML; Kansas City University of Medicine and Biosciences, Zulfiqar H; Hamad Medical Corporation, Doha, Qatar
Jazyk: angličtina
Zdroj: 2022 Jan.
Abstrakt: First-degree burns are superficial burns involving the epidermal layer of skin. The skin is the largest organ of the human body, with its weight comprising up 16% of total body weight. The layers of skin consist of the epidermis, dermis, and hypodermis. The functions of skin include providing a protective barrier, regulating temperature, controlling evaporation, excretion, and sensing heat, cold, pressure, and touch. Embryological Origin The epidermis arises from surface ectoderm with specialized cells such as antigen-processing Langerhans cells of bone marrow origin, and melanocytes and pressure-sensing Merkel cells from neural crest origin. Blood supply is from diffusion through the dermoepidermal junction. The histology of the epidermis is of a stratified, squamous epithelium that is composed of keratinocytes. The epidermis can further be stratified by layers which are: stratum germinativum, stratum spinosum, stratum granulosum, and stratum corneum.
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Databáze: MEDLINE