Acetylated Furostene Glycosides from Solanum gilo Fruits.

Autor:	Tchoupang EN; Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde 1, Yaounde, Cameroon., Reder C; Department of Pharmacognosy, University of Vienna, Vienna, Austria., Ateba SB; Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde 1, Yaounde, Cameroon., Zehl M; Department of Pharmacognosy, University of Vienna, Vienna, Austria.; Department of Analytical Chemistry, University of Vienna, Vienna, Austria., Kählig H; Institute of Organic Chemistry, University of Vienna, Vienna, Austria., Njamen D; Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde 1, Yaounde, Cameroon., Höller F; Department of Pharmacognosy, University of Vienna, Vienna, Austria., Glasl-Tazreiter S; Department of Pharmacognosy, University of Vienna, Vienna, Austria., Krenn L; Department of Pharmacognosy, University of Vienna, Vienna, Austria.
Jazyk:	angličtina
Zdroj:	Planta medica [Planta Med] 2017 Oct; Vol. 83 (14-15), pp. 1227-1232. Date of Electronic Publication: 2017 Jul 18.
DOI:	10.1055/s-0043-116491
Abstrakt:	In continuation of our work on a traditional mixture of spices called "Nkui", used in Cameroon for its influence on women's reproductive health, we investigated the chemical composition of Solanum gilo , one component of "Nkui". A methanolic extract was studied in detail. After dereplication of several known compounds, two furo-5-stene-derived saponin glycosides with acetylated sugar moieties were isolated. By extensive 1- and 2D NMR experiments and HR-MS and GC-MS methods, the structures were elucidated as 26-[(3‴,4‴,6‴-tri-O-acetyl)- β -D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3 β -yl-O- α -L-rhamnopyranosyl-(1″→2')- β -D-glucopyranoside ( A ) and 26-[(3‴,4‴,6‴-tri-O-acetyl)- β -D-glucopyranosyloxy]-22-hydroxyfurost-5-en-3 β -yl-[O- α -L-rhamnopyranosyl-(1''''→4')-O- α -L-rhamnopyranosyl-(1″→2')]- β -D-glucopyranoside ( B ), both new natural compounds. Competing Interests: Conflict of Interest: The authors declare no conflict of interest. (Georg Thieme Verlag KG Stuttgart · New York.)
Databáze:	MEDLINE
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