Pancreatic T/histiocyte-rich large B-cell lymphoma: A case report and review of literature.

Autor:	Zheng SM; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Zhou DJ; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Chen YH; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Jiang R; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Wang YX; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Zhang Y; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Xue HL; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Wang HQ; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Mou D; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China., Zeng WZ; Shu-Mei Zheng, De-Jiang Zhou, Yun-Xia Wang, Yong Zhang, Hong-Li Xue, Hai-Qiong Wang, Dong Mou, Wei-Zheng Zeng, Department of Gastroenterology and Hepatology, Chengdu Military General Hospital, Chengdu 610083, Sichuan Province, China.
Jazyk:	angličtina
Zdroj:	World journal of gastroenterology [World J Gastroenterol] 2017 Jun 28; Vol. 23 (24), pp. 4467-4472.
DOI:	10.3748/wjg.v23.i24.4467
Abstrakt:	Primary pancreatic lymphoma (PPL) is an extremely rare form of extranodal malignant lymphoma. The most common histological subtype of PPL is diffuse large B cell lymphoma (DLBCL). In rare cases, PPL can also present as follicular lymphoma, small lymphocytic lymphoma, and T cell lymphoma either of non-Hodgkin's lymphoma or of Hodgkin's lymphoma. T-cell/histiocyte-rich large B-cell lymphoma (T/HRBCL) is an uncommon morphologic variant of DLBCL with aggressive clinical course, it is predominantly a nodal disease, but extranodal sites such as bone marrow, liver, and spleen can be involved. Pancreatic involvement of T/HRBCL was not presented before. Herein, we report a 48-year-old male who was hospitalized with complaints of jaundice, dark brown urine, pale stools, and nausea. The radiological evaluation revealed a pancreatic head mass and, following operative biopsy, the tumor was diagnosed as T/HRBCL. The patient achieved remission after six cycles of CHOP chemotherapy. Therefore, T/HRBCL can be treated similarly to the stage-matched DLBCL and both of them get equivalent outcomes after chemotherapy. Competing Interests: Conflict-of-interest statement: Authors have no conflict of interest to disclose.
Databáze:	MEDLINE
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