Treatment of Pediatric IgG4-Related Orbital Disease With TNF-α Inhibitor.

Autor: Jalaj S; Columbia University Medical Center/Harkness Eye Institute, New York, New York, U.S.A., Dunbar K, Campbell A, Kazim M
Jazyk: angličtina
Zdroj: Ophthalmic plastic and reconstructive surgery [Ophthalmic Plast Reconstr Surg] 2018 Jan/Feb; Vol. 34 (1), pp. e10-e12.
DOI: 10.1097/IOP.0000000000000959
Abstrakt: The authors describe a 9-year-old female who presented with swelling, proptosis, and tenderness of the right upper eyelid and MRI imaging demonstrating right lacrimal gland enlargement. After failing treatment with corticosteroids, the patient underwent a biopsy that was consistent with IgG4-related orbital disease. She was subsequently successfully treated with adalimumab (TNF-α inhibitor). This is the first case report of the successful use of a TNF-α inhibitor for the treatment of IgG4-related orbital disease in a child.
Databáze: MEDLINE