Spinal cord infarction in a sick neonate from predominant haemorrhagic aetiology: a case report.

Autor:	Kulshrestha R; The Midland Centre of Spinal Injuries, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Shropshire, UK., Chowdhury JR; The Midland Centre of Spinal Injuries, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Shropshire, UK., Lalam RK; The Midland Centre of Spinal Injuries, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Shropshire, UK., Kiely NT; The Midland Centre of Spinal Injuries, Robert Jones and Agnes Hunt Orthopaedic Hospital NHS Trust, Shropshire, UK.
Jazyk:	angličtina
Zdroj:	Spinal cord series and cases [Spinal Cord Ser Cases] 2017 Jul 06; Vol. 3, pp. 17038. Date of Electronic Publication: 2017 Jul 06 (Print Publication: 2017).
DOI:	10.1038/scsandc.2017.38
Abstrakt:	Introduction: Spinal cord injuries in new born infants following a traumatic delivery or umbilical cord catheterisation due to thromboembolism are well known. Cases with atraumatic acute onset of neonatal paraplegia have also been described in preterm babies or babies born small for gestational age with a stormy postnatal course related to ischaemic aetiology. We describe a rare case of infarction of the spinal cord from a predominant haemorrhagic aetiology. Case Presentation: A term female baby, first child of unrelated parents, was born by normal vaginal delivery. She had meconium aspiration at birth, leading to severe respiratory distress, requiring neonatal intensive care admission. At 2 weeks, she developed new flaccid paraplegia. MRI scan of the spine showed haemorrhagic infarction of the spinal cord from the level of thoracic inlet, vertebral level C7-T1. A follow-up MRI scan at 11 months revealed severe atrophy of the cord distal to C6. At 3 years of age, she had good upper-limb function, diaphragmatic breathing and flaccid paralysis of lower limbs. Discussion: In an acutely unwell term infant with symptoms of paralysis or spinal cord damage, haemorrhagic infarction needs to be considered in the differential diagnosis. To our knowledge, this is the first reported case of spinal cord injury in a term infant with a haemorrhagic lesion, and it helps to understand the pathogenesis of nontraumatic insult. Competing Interests: The authors declare no conflict of interest.
Databáze:	MEDLINE
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