| Autor: |
van der Vos CS; Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands.; MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands., Koopman D; MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede, The Netherlands.; Department of Nuclear Medicine, Isala Hospital, Zwolle, The Netherlands., Rijnsdorp S; Department of Medical Physics, Catharina Hospital, Eindhoven, The Netherlands., Arends AJ; Department of Medical Physics, Catharina Hospital, Eindhoven, The Netherlands., Boellaard R; Department of Nuclear Medicine & Molecular Imaging, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.; Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands., van Dalen JA; Department of Nuclear Medicine, Isala Hospital, Zwolle, The Netherlands.; Department of Medical Physics, Isala, Zwolle, The Netherlands., Lubberink M; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.; Department of Medical Physics, Uppsala University Hospital, Uppsala, Sweden., Willemsen ATM; Department of Nuclear Medicine & Molecular Imaging, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands., Visser EP; Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, The Netherlands. eric.visser@radboudumc.nl. |
| Abstrakt: |
In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent 18 F-fluorodeoxyglucose (FDG) activity. Also, hardware developments such as continuous bed motion (CBM), (digital) solid-state photodetectors and combined PET and magnetic resonance (MR) systems are explained. These novel techniques have a significant impact on cancer imaging, as they result in better image quality, improved small lesion detectability, and more accurate quantification of radiopharmaceutical uptake. This influences cancer diagnosis and staging, as well as therapy response monitoring and radiotherapy planning. Finally, the possible impact of these developments on the European Association of Nuclear Medicine (EANM) guidelines and EANM Research Ltd. (EARL) accreditation for FDG-PET/CT tumor imaging is discussed. |
