[Olmesartan-associated enteropathy: attention to an emerging iatrogenic phenomenon].

Autor: Modesto Dos Santos JL; Servicio de Medicina Interna, Complejo Hospitalario de Navarra. jmodestosantos@gmail.com., González Recio P, Terry López OA, Leturia Frade I, Aguiar Losada B, Elejalde Guerra JI
Jazyk: Spanish; Castilian
Zdroj: Anales del sistema sanitario de Navarra [An Sist Sanit Navar] 2017 Aug 31; Vol. 40 (2), pp. 291-294. Date of Electronic Publication: 2017 Aug 31.
DOI: 10.23938/ASSN.0021
Abstrakt: Olmesartan is an angiotensin II type 1 receptor blocker commonly used in the treatment of hypertension. Several cases of sprue-like enteropathy associated with the use of this drug have been described which, even with important signs and limitations for the patient, present a full recovery after discontinuing the use of olmesartan. The case of a 64 year-old patient is presented, diagnosed with hypertension, under treatment with olmesartan-amlodipine, with chronic diarrhoea and villous atrophy on intestinal biopsies without diagnostic criteria for celiac disease and with complete remission after suspending discontinuing the use of olmesartan. Based on the clinical features presented by the case reported, the clinical and anatomopathological findings are described as well as the evolution of drug-induced enteropathy.
Databáze: MEDLINE