Applications of Functional Amyloids from Fungi: Surface Modification by Class I Hydrophobins.
| Autor: | Piscitelli A; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. apiscite@unina.it., Cicatiello P; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. paola.cicatiello@unina.it., Gravagnuolo AM; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. alfredo.gravagnuolo@manchester.ac.uk.; Division of Pharmacy and Optometry, Faculty of Biology, Medicine and Health, The University of Manchester, M13 9PT Manchester, UK. alfredo.gravagnuolo@manchester.ac.uk., Sorrentino I; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. ilaria.sorrentino@unina.it., Pezzella C; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. cpezzella@unina.it., Giardina P; Department of Chemical Sciences, Università degli Studi di Napoli Federico II, Complesso Universitario Monte S. Angelo, Via Cintia 4, 80126 Naples, Italy. giardina@unina.it. |
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| Jazyk: | angličtina |
| Zdroj: | Biomolecules [Biomolecules] 2017 Jun 26; Vol. 7 (3). Date of Electronic Publication: 2017 Jun 26. |
| DOI: | 10.3390/biom7030045 |
| Abstrakt: | Class I hydrophobins produced from fungi are amongst the first proteins recognized as functional amyloids. They are amphiphilic proteins involved in the formation of aerial structures such as spores or fruiting bodies. They form chemically robust layers which can only be dissolved in strong acids. These layers adhere to different surfaces, changing their wettability, and allow the binding of other proteins. Herein, the modification of diverse types of surfaces with Class I hydrophobins is reported, highlighting the applications of the coated surfaces. Indeed, these coatings can be exploited in several fields, spanning from biomedical to industrial applications, which include biosensing and textile manufacturing. Competing Interests: The authors declare no conflicts of interest. |
| Databáze: | MEDLINE |
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