Paroxysmal nocturnal hemoglobinuria terminating as erythroleukemia.

Autor: Cowall DE, Pasquale DN, Dekker P
Jazyk: angličtina
Zdroj: Cancer [Cancer] 1979 May; Vol. 43 (5), pp. 1914-6.
DOI: 10.1002/1097-0142(197905)43:5<1914::aid-cncr2820430549>3.0.co;2-q
Abstrakt: A case of a patient who developed erythroleukemia 3 years into the course of paroxysmal nocturnal hemoglobinuria (PNH) is presented. A case of erythroleukemia with a positive sucrose lysis test has been reported, but our case appears to be the first with a long clinical course of PNH evolving into erythroleukemia. The association between these two diseases, their possible clonal origin, and how they fit into the myelodysplastic syndromes are discussed.
Databáze: MEDLINE