The visual system in infants with microcephaly related to presumed congenital Zika syndrome.

Autor: Verçosa I; CAVIVER NGO Clinic, Fortaleza, Ceara, Brazil., Carneiro P; CAVIVER NGO Clinic, Fortaleza, Ceara, Brazil., Verçosa R; CAVIVER NGO Clinic, Fortaleza, Ceara, Brazil., Girão R; CAVIVER NGO Clinic, Fortaleza, Ceara, Brazil., Ribeiro EM; Albert Sabin Pediatric Hospital, Fortaleza, Ceara, Brazil., Pessoa A; Albert Sabin Pediatric Hospital, Fortaleza, Ceara, Brazil., Almeida NG; University of the State of Ceara(UECE), Fortaleza, Ceara, Brazil., Verçosa P; CAVIVER NGO Clinic, Fortaleza, Ceara, Brazil., Tartarella MB; Department of Ophthalmology and Visual Science, Federal University of São Paulo (UNIFESP), Sao Paulo, SP, Brazil. Electronic address: tartarella@yahoo.com.
Jazyk: angličtina
Zdroj: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus [J AAPOS] 2017 Aug; Vol. 21 (4), pp. 300-304.e1. Date of Electronic Publication: 2017 Jun 23.
DOI: 10.1016/j.jaapos.2017.05.024
Abstrakt: Purpose: To describe and analyze ocular features in infants with microcephaly due to presumed congenital Zika syndrome.
Methods: Ophthalmologic evaluation, including indirect ophthalmoscopy and eye fundus imaging, visual acuity testing with Teller Acuity Cards, and strabismus assessment were performed in infants with microcephaly at a nongovernmental organization clinic for visually disabled children.
Results: A total of 70 infants with microcephaly were referred to the clinic. Of these, 25 (mean age, 3 months; 14 males) had ophthalmologic changes: 18 (26%) had intraocular abnormalities, including macular chorioretinal atrophy, mottled retinal pigment epithelium and optic nerve pallor; 7 patients (10%) had strabismus or nystagmus without intraocular abnormalities. Visual acuity was below normal range in all 11 infants tested.
Conclusions: Ophthalmologic abnormalities occurred in 36% of the patients. Macular circumscribed chorioretinal atrophy, focal mottled retinal pigment epithelium, optic nerve pallor, early-onset strabismus, nystagmus and low visual acuity were common ophthalmological features in infants with microcephaly due to presumed congenital Zika syndrome.
(Copyright © 2017 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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