New insights into the burden and costs of multiple sclerosis in Europe: Results for Portugal.

Autor:	Sá MJ; Department of Neurology, Centro Hospitalar de S. João, Porto, Portugal., Kobelt G; European Health Economics, Mulhouse, France., Berg J; Mapi Group, Stockholm, Sweden., Capsa D; Mapi Group, Stockholm, Sweden., Dalén J; Mapi Group, Stockholm, Sweden.
Jazyk:	angličtina
Zdroj:	Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2017 Aug; Vol. 23 (2_suppl), pp. 143-154.
DOI:	10.1177/1352458517708667
Abstrakt:	Background: In order to assess the value of management strategies in multiple sclerosis (MS), outcome data have to be combined with cost data. This, in turn, requires that cost data be regularly updated. Objective and Methods: This study is part of a cross-sectional retrospective study in 16 countries collecting current data on resource consumption, work capacity and health-related quality of life (HRQoL). Descriptive analyses are presented by level of severity; costs are estimated in the societal perspective, in EUR 2015. Results: A total of 535 patients (mean age 48.5 years) participated; 92% were below retirement age and of these, 43% were employed. Employment was related to disease severity, and MS was felt to affect productivity at work by 72% of patients, most often through fatigue. Overall, 98% and 74% of patients felt that fatigue and cognition were a problem. Mean utility and costs were 0.756 and €16,500 at the Expanded Disability Status Scale (EDSS) 0-3, 0.572 and €28,700 at EDSS 4-6.5 and 0.206 and €34,400 at EDSS 7-9. The average cost of a relapse was estimated at €2930. Conclusion: This study illustrates the burden of MS on Portuguese patients and provides current data that are important for the development of health policies.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu