| Autor: |
Nikuradze VO, Rozhanets VV, Kozlovskaia MM, Val'dman AV |
| Jazyk: |
ruština |
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny [Biull Eksp Biol Med] 1985 Sep; Vol. 100 (9), pp. 275-7. |
| Abstrakt: |
It has been shown that the 15-day stressing of rats by means of stochastic footshock combined with light flashes leads to a relatively stable "behavioral depression". Twenty-four hours after the last exposure to stress crude synaptosomes isolated from the whole brain demonstrated an increase in the KD of 3H-dihydroalprenolol specific binding and a lowering of the Bmax of 3H-WB-4101 specific binding sites. Specific binding of 3H-flunitrazepam changes inconclusively: the decrease in the KD is followed by a reduction in the concentration of receptors. Specific binding of 3H-imipramine by brain membranes remains unchanged under the above conditions. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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