[Neurohormonal changes during the growth of metastatic Lewis carcinoma in C57Bl mice].

Autor: Shmal'ko IuP, Pridatko OE, Smelkova MI
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1985 May-Jun; Vol. 31 (3), pp. 57-60.
Abstrakt: Functions of adrenal gland cortex, mediator system of brain and of sympathoadrenal system, including hormone formation in medullar layer of adrenal glands, were studied in mice of C57BL strain with growing metastatic Lewis carcinoma. The neurohormonal activity was distinctly inhibited under conditions of stress within the period of adaptation to the tumor development (I-14 days after the carcinoma inoculation) as well as in development of metastases (21 day of the tumor growth). Excessive stimulation of the systems studied as well as their exhaustion, might cause a distinct augmenting effect on the tumor growth and development of metastases.
Databáze: MEDLINE