Glycosaminoglycan-based resorbable polymer composites in tissue refurbishment.

Autor:	Gulati K; Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India., Meher MK; Centre for Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India., Poluri KM; Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.; Centre for Nanotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
Jazyk:	angličtina
Zdroj:	Regenerative medicine [Regen Med] 2017 Apr; Vol. 12 (4), pp. 431-457. Date of Electronic Publication: 2017 Jun 16.
DOI:	10.2217/rme-2017-0012
Abstrakt:	Regeneration of tissue structure with the aid of bioactive polymer matrices/composites and scaffolds for respective applications is one of the emerging areas of biomedical engineering. Recent advances in conjugated glycosaminoglycan (GAG) hybrids using natural and synthetic polymers have opened new avenues for producing a wide variety of resorbable polymer matrices. These hybrid scaffolds are low-immunogenic, highly biocompatible and biodegradable with incredible mechanical and tensile properties. GAG-based resorbable polymeric matrices are being exploited in migration of stem cells, cartilage and bone replacement/regeneration and production of scaffolds for various tissue engineering applications. In the current review, we will discuss the role of GAG-based resorbable polymer matrices in the field of regenerative medicine.
Databáze:	MEDLINE
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