| Autor: |
Antonarakis SE, Copeland KL, Carpenter RJ Jr, Carta CA, Hoyer LW, Caskey CT, Toole JJ, Kazazian HH Jr |
| Jazyk: |
angličtina |
| Zdroj: |
Lancet (London, England) [Lancet] 1985 Jun 22; Vol. 1 (8443), pp. 1407-9. |
| DOI: |
10.1016/s0140-6736(85)91842-2 |
| Abstrakt: |
Cloned factor VIII deoxyribose nucleic acid (DNA) sequences were used as probes in the prenatal diagnosis of haemophilia A. Fetal DNA from cultured amniotic fluid cells was examined for a DNA polymorphism within the factor VIII gene which marked the haemophilia A gene in the pregnant obligate carrier. The fetus was predicted to be an affected male, and the diagnosis of haemophilia A was confirmed both in utero and after termination of the pregnancy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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