Effects of L-glutamine on rectal temperature and some markers of oxidative stress in Red Sokoto goats during the hot-dry season.

Autor: Ocheja OB; Department of Physiology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, PMB 1045, Nigeria. boodos24@yahoo.com.; Department of Veterinary Physiology, Faculty of Veterinary Medicine, University of Benin, Benin City, Nigeria. boodos24@yahoo.com., Ayo JO; Department of Physiology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, PMB 1045, Nigeria., Aluwong T; Department of Physiology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, PMB 1045, Nigeria., Minka NS; Department of Physiology, Faculty of Veterinary Medicine, Ahmadu Bello University, Zaria, PMB 1045, Nigeria.
Jazyk: angličtina
Zdroj: Tropical animal health and production [Trop Anim Health Prod] 2017 Aug; Vol. 49 (6), pp. 1273-1280. Date of Electronic Publication: 2017 Jun 12.
DOI: 10.1007/s11250-017-1325-5
Abstrakt: The experiment investigated the ameliorative effects of L-glutamine administration on rectal temperature (RT), erythrocyte osmotic fragility (EOF), serum antioxidant enzyme activities and malondialdehyde (MDA) concentration in Red Sokoto goats during the hot-dry season. Twenty eight healthy Red Sokoto goats, comprising 14 experimental (administered 0.2 g/kg of L-glutamine dissolved in 10 mL of distilled water, once daily for 21 days) and 14 control (administered equivalent of distilled water) goats served as subjects. Rectal temperature (measured at 6:00, 13:00 and 18:00 h) and blood samples (taken at 8:00 h) were obtained from all subjects weekly, before, during and after L-glutamine administration. Data obtained were compared using one-way repeated-measures ANOVA, followed by Tukey's post-hoc test. The dry-bulb temperature, relative humidity and temperature-humidity index for the study period ranged between 24.0 and 37.5 °C, 26.0 and 84.0% and 73.0 and 86.3, respectively. L-glutamine administration decreased (P < 0.05) RT, EOF and MDA and increased superoxide dismutase (SOD) activity in experimental group, compared to controls during weeks 1, 2 and 3. Glutathione peroxidase (GPx) and catalase activities were higher (P < 0.05) in the experimental group than in the controls only during week 1 of L-glutamine administration. In conclusion, L-glutamine administration mitigated increases in RT, EOF and serum MDA concentration and enhanced serum SOD, GPx and catalase activities and may be beneficial in heat-stressed goats during the hot-dry season.
Databáze: MEDLINE
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