A rare association of ganglioglioma and cavernous malformation: Report of two cases and literature review.
| Autor: | Carangelo BR; Department of Neurological and Sensory Sciences, Division of Neurosurgery, Siena University Hospital, Siena, Italy., Muscas G; Department of Medicine, Surgery, and Neurosciences, Section of Neurosurgery, University of Siena, Siena, Italy., Miracco C; Department of Medicine, Surgery, and Neurosciences, Section of Human Pathology, University of Siena, Siena, Italy., Muzii VF; Department of Medicine, Surgery, and Neurosciences, Section of Neurosurgery, University of Siena, Siena, Italy. |
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| Jazyk: | angličtina |
| Zdroj: | Surgical neurology international [Surg Neurol Int] 2017 May 26; Vol. 8, pp. 94. Date of Electronic Publication: 2017 May 26 (Print Publication: 2017). |
| DOI: | 10.4103/2152-7806.207115 |
| Abstrakt: | Background: Some glial tumors have been observed in association with different types of vascular malformations of the brain (angiogliomas). However, the association of ganglioglioma with other vascular malformations is extremely rare, with only few cases reported in the literature, one of which is referred to as "angioganglioglioma." Case Description: Two patients presented with acute onset of neurological symptoms, with magnetic resonance imaging (MRI) finding of cavernoma of the left middle cerebellar penduncle, and small mass of the chiasmatic region, respectively. After microsurgical excision, histopathological examination revealed mixed ganglioglioma and cavernous malformation in both cases. Postoperative course was uneventful, and follow-up MRI showed complete removal of the tumor with no recurrence after 4 years. Conclusions: Angiogliomas are very uncommon tumors. In literature, we found different interpretations of such lesions, although they should most probably be considered as distinct pathological entities. Although the association of ganglioglioma with cavernoma is extremely rare, it could be considered as a most peculiar form of angioglioma, and supports the existence of angioganglioglioma. Competing Interests: There are no conflicts of interest. |
| Databáze: | MEDLINE |
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