Diet quality is associated with reduced incidence of cancer and self-reported chronic disease: Observations from Alberta's Tomorrow Project.

Autor: Solbak NM; Cancer Measurement, Outcomes, Research and Evaluation, CancerControl Alberta, Alberta Health Services, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada. Electronic address: nathan.solbak@ahs.ca., Xu JY; Cancer Measurement, Outcomes, Research and Evaluation, CancerControl Alberta, Alberta Health Services, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada., Vena JE; Cancer Measurement, Outcomes, Research and Evaluation, CancerControl Alberta, Alberta Health Services, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada., Csizmadi I; Departments of Oncology and Community Health Sciences, Cumming School of Medicine, University of Calgary, Health Sciences Centre, Foothills Campus, 3330 Hospital Dr NW, Calgary, AB T2N 4N1, Canada., Whelan HK; Cancer Measurement, Outcomes, Research and Evaluation, CancerControl Alberta, Alberta Health Services, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada., Robson PJ; Cancer Measurement, Outcomes, Research and Evaluation, CancerControl Alberta, Alberta Health Services, 1820 Richmond Rd SW, Calgary, AB T2T 5C7, Canada; Department of Agricultural, Food and Nutritional Science, Faculty of Agricultural, Life and Environmental Sciences, University of Alberta, 410 Agriculture/Forestry Centre, Edmonton, AB T6G 2P5, Canada.
Jazyk: angličtina
Zdroj: Preventive medicine [Prev Med] 2017 Aug; Vol. 101, pp. 178-187. Date of Electronic Publication: 2017 Jun 07.
DOI: 10.1016/j.ypmed.2017.06.009
Abstrakt: The objective of this study was to assess diet quality using the Healthy Eating Index-2005 Canada (HEI-2005-Canada) and its association with risk of cancer and chronic disease in a sample of Alberta's Tomorrow Project (ATP) participants. Food frequency questionnaires completed by 25,169 participants (38% men; mean age 50.3 (9.2)) enrolled between 2000 and 2008 were used to calculate HEI-2005-Canada scores. Data from a subset of participants (n=10,735) who reported no chronic disease at enrollment were used to investigate the association between HEI-2005-Canada score and development of self-reported chronic disease at follow-up (2008). Participants were divided into HEI-2005-Canada score quartiles. Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for cancer and chronic disease incidence. In this cohort, mean HEI-2005-Canada scores for men and women were 50.9 and 55.5 (maximum range 0-100), respectively. In men, higher HEI-2005-Canada score (Q4 vs. Q1) was associated with lower cancer risk (HR (95% CI) 0.63 (0.49-0.83)) over the course of follow-up (mean (SD)=10.4 (2.3) years); the same was not observed in women. In contrast, higher overall HEI-2005-Canada score (Q4 vs. Q1) was associated with lower risk of self-reported chronic disease (0.85 (0.75-0.97)) in both men and women over follow-up (4.2 (2.3) years). In conclusion, in this cohort better diet quality was associated with a lower risk of cancer in men and lower risk of chronic disease in both sexes. Future studies with longer follow-up and repeated measures of diet may be helpful to elucidate sex-specific associations between dietary quality and disease outcomes.
(Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: