Message in a Bottle: Dialog between Intestine and Skin Modulated by Probiotics.

Autor: Friedrich AD; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología, 1053 Buenos Aires, Argentina. afriedrich.bioq@gmail.com., Paz ML; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología, 1053 Buenos Aires, Argentina. mlpaz@ffyb.uba.ar.; CONICET-Universidad de Buenos Aires, Instituto de Estudios de la Inmunidad Humoral (IDEHU), LIBAP, 1053 Buenos Aires, Argentina. mlpaz@ffyb.uba.ar., Leoni J; CONICET-Universidad de Buenos Aires, Instituto de Estudios de la Inmunidad Humoral (IDEHU), LIBAP, 1053 Buenos Aires, Argentina. jleoni@ffyb.uba.ar., González Maglio DH; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Cátedra de Inmunología, 1053 Buenos Aires, Argentina. danielgm@ffyb.uba.ar.; CONICET-Universidad de Buenos Aires, Instituto de Estudios de la Inmunidad Humoral (IDEHU), LIBAP, 1053 Buenos Aires, Argentina. danielgm@ffyb.uba.ar.
Jazyk: angličtina
Zdroj: International journal of molecular sciences [Int J Mol Sci] 2017 Jun 09; Vol. 18 (6). Date of Electronic Publication: 2017 Jun 09.
DOI: 10.3390/ijms18061067
Abstrakt: At the beginning, probiotics were used exclusively for gastrointestinal conditions. However, over the years, evidence has shown that probiotics exert systemic effects. In this review article, we will summarize recent reports that postulate probiotic treatment as an efficient one against skin pathologies, such as cancer, allergy, photoaging and skin infections. The focus will be restricted to oral probiotics that could potentially counteract the ultraviolet irradiation-induced skin alterations. Moreover, the possible underlying mechanisms by which probiotics can impact on the gut and exert their skin effects will be reviewed. Furthermore, how the local and systemic immune system is involved in the intestine-cutaneous crosstalk will be analyzed. In conclusion, this article will be divided into three core ideas: (a) probiotics regulate gut homeostasis; (b) gut and skin homeostasis are connected;
Competing Interests: The authors declare no conflict of interest.
((c) probiotics are a potentially effective treatment against skin conditions.)
Databáze: MEDLINE
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