Vulvar lichen sclerosus in women is associated with lower urinary tract symptoms.

Autor: Christmann-Schmid C; Department of Gynecology and Obstetrics, Cantonal Hospital of Lucerne, Lucerne, Switzerland. corina.christmann@luks.ch.; Department for Urogynecology, Cantonal Hospital of Lucerne, 6000, Lucerne, Switzerland. corina.christmann@luks.ch., Hediger M; Department of Gynecology and Obstetrics, Cantonal Hospital of Lucerne, Lucerne, Switzerland., Gröger S; Department of Gynecology and Obstetrics, Cantonal Hospital of Lucerne, Lucerne, Switzerland., Krebs J; Clinical Trial Unit, Swiss Paraplegic Centre, Nottwil, Switzerland., Günthert AR; Department of Gynecology and Obstetrics, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
Jazyk: angličtina
Zdroj: International urogynecology journal [Int Urogynecol J] 2018 Feb; Vol. 29 (2), pp. 217-221. Date of Electronic Publication: 2017 Jun 07.
DOI: 10.1007/s00192-017-3358-8
Abstrakt: Introduction and Hypothesis: Lichen sclerosus (LS) is thought to be primarily a disease of postmenopausal women. Little is reported about lower urinary tract symptoms (LUTS) in association with LS. The aims of this study were to evaluate the odds of having LS-associated LUTS and to identify the predominant type of LS-associated bladder dysfunction.
Methods: This was a cross-sectional study with two cohorts investigating the association between LS and LUTS and the predominant type of LS-associated bladder dysfunction.
Results: The odds of LUTS in women with LS were more than four times higher than in women without LS (OR 4.5, 95% CI 2.6-8.0; p < 0.0001). There was no significant difference in the occurrence of LUTS between women who experienced the first LS symptoms before and after the age of 50 years (36% and 53%, respectively, p = 0.14), or in the occurrence of the different types of LUTS between women with and without LS (p = 0.3). The most common type of LUTS was overactive bladder (OAB) in both women with LS (67.3%) and without LS (60%). The most prevalent type of LS-associated LUTS was OAB.
Conclusions: The odds of developing LUTS (self-reported) are four times higher in women with LS than in those without. The predominant type of LUTS in women with and without LS is OAB.
Databáze: MEDLINE
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