How changes in physical activity relate to fatigue interference, mood, and quality of life during treatment for non-metastatic breast cancer.

Autor: Fisher HM; Department of Psychology, University of Miami, Coral Gables, FL 33124, United States. Electronic address: hannah.fisher@miami.edu., Jacobs JM; Massachusetts General Hospital, Center for Psychiatric Oncology and Behavioral Sciences, Boston, MA 02114, United States; Harvard Medical School, Boston, MA 02115, United States., Taub CJ; Department of Psychology, University of Miami, Coral Gables, FL 33124, United States., Lechner SC; Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, United States; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, United States., Lewis JE; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, United States., Carver CS; Department of Psychology, University of Miami, Coral Gables, FL 33124, United States; Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, United States., Blomberg BB; Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, United States; Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, United States., Antoni MH; Department of Psychology, University of Miami, Coral Gables, FL 33124, United States; Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, United States; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, United States.
Jazyk: angličtina
Zdroj: General hospital psychiatry [Gen Hosp Psychiatry] 2017 Nov; Vol. 49, pp. 37-43. Date of Electronic Publication: 2017 May 29.
DOI: 10.1016/j.genhosppsych.2017.05.007
Abstrakt: Objective: Physical activity (PA) following surgery for breast cancer may improve depressive symptoms and quality of life (QoL) via reduction in fatigue-related daily interference (FRDI). Less is known about how change in PA may relate to these psychosocial factors throughout the course of treatment. In a secondary analysis of a previous psychosocial intervention trial, we examined relationships between change in PA, depressive symptoms, and functional QoL, as mediated by change in FRDI, and whether naturally occurring change in PA provided benefit independent of the intervention.
Method: Women (N=240) with non-metastatic stage 0-III breast cancer were randomized to cognitive-behavioral stress management (CBSM) or a control 2-10weeks post-surgery. PA, FRDI, clinician-rated depressive symptoms, self-reported depressed mood, and functional QoL were assessed at baseline and three months post-intervention.
Results: Increased PA was associated with reductions in clinician-rated depressive symptoms, depressed mood, and improved QoL, mediated by a reduction in FRDI. This was above and beyond the effect of CBSM.
Conclusions: Increased PA may mitigate FRDI and improve depressive symptoms and functional QoL for women undergoing breast cancer treatment, beyond effects of a psychosocial intervention. Benefits of an integrated PA and psychosocial approach should be investigated further.
(Copyright © 2017 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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