| Autor: |
Mehra MK; Department of Chemistry, Birla Institute of Technology and Science, Pilani 333 031, Rajasthan, India. dalipk@pilani.bits-pilani.ac.in., Tantak MP, Arun V, Kumar I, Kumar D |
| Jazyk: |
angličtina |
| Zdroj: |
Organic & biomolecular chemistry [Org Biomol Chem] 2017 Jun 14; Vol. 15 (23), pp. 4956-4961. |
| DOI: |
10.1039/c7ob00940b |
| Abstrakt: |
Regioselective construction of crucial C-N and C-O bonds leading to N-arylquinolones and aryloxyquinolines has been accomplished by employing easily accessible diaryliodonium salts and quinolones in water under metal- and ligand-free conditions. This operationally simple strategy is significant due to mild reaction conditions, high product yields, recyclability of released iodoarenes and scalability to the gram level. The practical utility of the developed protocol was proved by the arylation of medicinally important heterocycles like acridin-9(10H)-one, 3-methylquinoxalin-2(1H)-one and 1H-benzo[d]imidazol-2(3H)-one. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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