Favourable Outcome in a 33-Year-Old Female with Acute Haemorrhagic Leukoencephalitis.

Autor: Solis WG; Department of Neurosurgery, John Hunter Hospital, New Lambton, New South Wales, Australia., Waller SE; Department of Neurology, John Hunter Hospital, New Lambton, New South Wales, Australia., Harris AK; Department of Anatomical Pathology, Pathology North Hunter, New Lambton, New South Wales, Australia., Sugo E; Department of Anatomical Pathology, Pathology North Hunter, New Lambton, New South Wales, Australia., Hansen MA; Department of Neurosurgery, John Hunter Hospital, New Lambton, New South Wales, Australia., Lechner-Scott J; Department of Neurology, John Hunter Hospital, New Lambton, New South Wales, Australia.
Jazyk: angličtina
Zdroj: Case reports in neurology [Case Rep Neurol] 2017 May 05; Vol. 9 (1), pp. 106-113. Date of Electronic Publication: 2017 May 05 (Print Publication: 2017).
DOI: 10.1159/000472706
Abstrakt: Background: Acute haemorrhagic leukoencephalitis (AHLE) is a rare and rapidly fatal disease of unknown aetiology. There is a paucity of literature on the presentation and management of this rare disease.
Case Description: We report the case of a 33-year-old female presenting with headache and left-sided apraxia. Imaging revealed a right-sided white matter lesion with extensive cytotoxic oedema. Pathology was suggestive of AHLE. She underwent an open excisional biopsy and was treated with high-dose corticosteroids. Three months since symptom onset she remains clinically well with resolving apraxia and radiological appearance.
Conclusion: This case may represent a milder spectrum of AHLE, which responded favourably to corticosteroids.
Databáze: MEDLINE