Age-related changes of microcirculation in pia mater of rats' sensorimotor cortex.

Autor:	Sokolova IB; I.V.Pavlov Institute of Physiology, RAS, Saint-Petersburg, Russian Federation; sib@kolt.infran.ru., Sergeev IV; I.V.Pavlov Institute of Physiology, RAS, Saint-Petersburg, Russian Federation; sib@kolt.infran.ru., Fedotova OR; Research Institute of Experimental Medicine, RAMS, Saint-Petersburg, Russian Federation., Melnikova NN; I.V.Pavlov Institute of Physiology, RAS, Saint-Petersburg, Russian Federation; sib@kolt.infran.ru., Dvoretsky DP; I.V.Pavlov Institute of Physiology, RAS, Saint-Petersburg, Russian Federation; sib@kolt.infran.ru.
Jazyk:	English; Russian
Zdroj:	Advances in gerontology = Uspekhi gerontologii [Adv Gerontol] 2016; Vol. 29 (4), pp. 567-572.
Abstrakt:	We studied the density of the microvascular network in the pia mater, the tissue perfusion and saturation of the oxygen of sensorimotor cortex of hypertensive rats of different ages. Our investigations shown that the microvascular density in the pia mater was not only decreased, but also was increased. The perfusion of sensorimotor cortex was reduced and tissue saturation was enlarged. By the age of 12 months orienting-exploratory rats behavior became worse significantly in all major indicators of the test «open field».
Databáze:	MEDLINE
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