Angiosome-Based Allografts: Vascularized Composite Allotransplantation for Tailored Subunit Reconstruction with Volkmann Ischemic Contracture as a Case in Point.

Autor:	Taylor GI; Melbourne, Victoria, Australia.; From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the PA-Southside Clinical School, School of Medicine, University of Queensland, Brisbane., Sparks DS; Melbourne, Victoria, Australia.; From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the PA-Southside Clinical School, School of Medicine, University of Queensland, Brisbane., Gascoigne AC; Melbourne, Victoria, Australia.; From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the PA-Southside Clinical School, School of Medicine, University of Queensland, Brisbane., Corlett RJ; Melbourne, Victoria, Australia.; From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the PA-Southside Clinical School, School of Medicine, University of Queensland, Brisbane., Ashton MW; Melbourne, Victoria, Australia.; From the Taylor Lab, Department of Anatomy and Neuroscience, University of Melbourne; and the PA-Southside Clinical School, School of Medicine, University of Queensland, Brisbane.
Jazyk:	angličtina
Zdroj:	Plastic and reconstructive surgery [Plast Reconstr Surg] 2017 Jun; Vol. 139 (6), pp. 1291e-1304e.
DOI:	10.1097/PRS.0000000000003360
Abstrakt:	Background: As we enter an age with new approaches to tissue reconstruction, the emphasis on the adage "like for like" has become even more relevant. This study illustrates the potential for several tailored vascularized composite allotransplantation reconstructive techniques and, in particular, for the management of Volkmann contracture. Methods: Twenty fresh cadaver dissections and 30 archival lead oxide radiographic studies were examined to (1) identify potential upper limb vascularized composite allotransplantation donor sites (i.e., elbow, forearm, and flexor tendon complex) and (2) demonstrate a "mock transplant" of the vascularized volar forearm allograft for a severe Volkmann ischemia defect. They were designed without skin to reduce antigenicity. Results: The elbow joint was supplied within the brachial angiosome and the flexor tendon complex of the flexor digitorum superficialis and flexor digitorum profundus by the superficial palmar arch of the ulnar angiosome. The forearm allograft of flexor muscles, median, ulnar, and anterior interosseous nerves, when harvested on the brachial vessels, was supplied within the radial, ulnar, and anterior interosseous angiosomes but could be based on the ulnar artery alone because of intramuscular connections with the other territories. A mock transplant was performed with a distal-to-proximal dissection of the allograft, facilitating the best and fastest technique. Conclusions: This application of the angiosome concept highlights the anatomical feasibility of the volar forearm vascularized composite allotransplantation donor site focusing on a complex subunit problem in the upper limb-severe Volkmann ischemic contracture. It demonstrates the potential use and immunologic advantage of subdivided and modified nonskin variations of vascularized composite allotransplantation in reconstructive transplantation surgery. Clinical Question/level of Evidence: Therapeutic, V.
Databáze:	MEDLINE
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