Primary Cutaneous Mucormycosis in an Extremely Preterm Infant Successfully Treated with Liposomal Amphotericin B.

Autor: Lowe CD; Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland., Sainato RJ; Department of Pediatric Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, Maryland., Stagliano DR; Department of Pediatric Infectious Diseases, Walter Reed National Military Medical Center, Bethesda, Maryland., Morgan MM; Department of Pediatrics, San Antonio Military Medical Center, San Antonio, Texas., Green BP; Department of Dermatology, Walter Reed National Military Medical Center, Bethesda, Maryland.
Jazyk: angličtina
Zdroj: Pediatric dermatology [Pediatr Dermatol] 2017 May; Vol. 34 (3), pp. e116-e119.
DOI: 10.1111/pde.13124
Abstrakt: Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions. This case highlights the importance of rapid and thorough evaluation of skin lesions when evaluating preterm infants and other immunocompromised patients, even when other sources of infection have been identified.
(Published 2017. This article is a U.S. Government work and is in the public domain in the USA.)
Databáze: MEDLINE
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