Signature of the Sleeper Cell: A Biomarker of HIV Latency Revealed.

Autor: Pillai SK; Blood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, CA, USA. Electronic address: satish.pillai@ucsf.edu., Deeks SG; Positive Health Program, University of California, San Francisco, CA, USA.
Jazyk: angličtina
Zdroj: Trends in immunology [Trends Immunol] 2017 Jul; Vol. 38 (7), pp. 457-458. Date of Electronic Publication: 2017 May 13.
DOI: 10.1016/j.it.2017.04.007
Abstrakt: HIV establishes a reservoir in latently infected T cells, and this reservoir has long hampered curative approaches. A recent study by Descours et al. identifies CD32a as a marker of latently infected T cells, potentially opening the way to the development of strategies that directly target this critical HIV reservoir.
(Copyright © 2017 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE