Initial observation of CIN2 does not appear to reduce quality of life in women under 25 years of age.

Autor: Taghavi K; Department of Obstetrics and Gynecology, Christchurch Women's Hospital, Christchurch, New Zealand., Morell S; Department of Obstetrics and Gynecology, University of Otago, Christchurch, New Zealand., Lamb J; Department of Obstetrics and Gynecology, Christchurch Women's Hospital, Christchurch, New Zealand., MacNab H; Department of Obstetrics and Gynecology, Christchurch Women's Hospital, Christchurch, New Zealand., Innes C; Department of Obstetrics and Gynecology, University of Otago, Christchurch, New Zealand., Coffey K; Department of Obstetrics and Gynecology, Dunedin Public Hospital, Dunedin, New Zealand., Williman J; Department of Population Health, University of Otago, Christchurch, New Zealand., Simcock B; Department of Obstetrics and Gynecology, Dunedin Public Hospital, Dunedin, New Zealand., Sykes P; Department of Obstetrics and Gynecology, Christchurch Women's Hospital, Christchurch, New Zealand.
Jazyk: angličtina
Zdroj: The Australian & New Zealand journal of obstetrics & gynaecology [Aust N Z J Obstet Gynaecol] 2017 Aug; Vol. 57 (4), pp. 473-478. Date of Electronic Publication: 2017 May 16.
DOI: 10.1111/ajo.12633
Abstrakt: Background: Although the patient perspective is implicit in the practice of medicine, research evaluating this remains scarce. In a climate where clinicians and policy-makers constantly strive to achieve more patient-centred models of care, this omission warrants attention.
Aim: To assess health-related quality of life (HrQoL) in women under 25 years of age with cervical intra-epithelial neoplasia grade 2 (CIN2) receiving conservative management (colposcopy follow-up, with treatment if necessary) compared with those receiving immediate excisional treatment with large loop excision of the transformation zone (LLETZ).
Methods: An observational study evaluating HrQoL was conducted at Christchurch Women's Hospital, New Zealand. Women undergoing conservative management for CIN2 were compared with those undergoing immediate excisional treatment in an age-matched sample. The Short Form Health Survey 12 version 2 (SF-12v2) was used to evaluate HrQoL. Secondary outcomes of anxiety and sexual function were also assessed.
Results: One hundred and four women with CIN2 participated in the study. Of these, 63 (60%) received conservative management and 41 (40%) received immediate excisional treatment with LLETZ. We found no significant difference in HrQoL between the groups in a multivariate regression analysis adjusted for parity, smoking and socioeconomic status. There were also no significant differences in sexual function or anxiety.
Conclusion: We found no difference in HrQoL by management strategy. Conservative management of CIN2 in women under 25 is unlikely to have an adverse impact on self-reported HrQoL, anxiety or sexual functioning compared with conventional management.
(© 2017 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.)
Databáze: MEDLINE
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