Novel Insights in Fetal Cardiomyopathy due to in utero Herpes Simplex Virus Infection.
| Autor: | Pahlitzsch TMJ; Department of Obstetrics, Charité Universitätsmedizin Berlin, Berlin, Germany., Helbig ET, Sarioglu N, Hinkson L, von Weizsäcker K, Henrich W |
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| Jazyk: | angličtina |
| Zdroj: | Fetal diagnosis and therapy [Fetal Diagn Ther] 2017; Vol. 42 (3), pp. 236-239. Date of Electronic Publication: 2017 May 16. |
| DOI: | 10.1159/000475814 |
| Abstrakt: | This is a case report of fatal cardiomyopathy in a fetus following maternal intrauterine infection with herpes simplex virus (HSV), despite the mother having no symptoms of an infection. The fetus showed signs of a disseminated infection affecting the heart, brain, lungs, liver, adrenal glands, and skin. HSV cardiomyopathy, characterized by vast necrosis, extensive calcifications, and inflammatory infiltration, was found to be the cause of intrauterine fetal death. To our knowledge, this is a unique report of an asymptomatic maternal nonprimary or recurrent HSV infection that induced a transmission of HSV resulting in extensive and fatal changes in the fetal heart. (© 2017 S. Karger AG, Basel.) |
| Databáze: | MEDLINE |
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